Contribution of Tumor Necrosis Factor Receptor 1 to Early Cell Death in Diabetic Retinopathy
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چکیده
منابع مشابه
Alix and ALG-2 are involved in tumor necrosis factor receptor 1-induced cell death.
Alix/AIP1 regulates cell death in a way involving interactions with the calcium-binding protein ALG-2 and with proteins of ESCRT (endosomal sorting complex required for transport). Using mass spectrometry we identified caspase-8 among proteins co-immunoprecipitating with Alix in dying neurons. We next demonstrated that Alix and ALG-2 interact with pro-caspase-8 and that Alix forms a complex wit...
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2009
ISSN: 1662-453X
DOI: 10.3389/conf.neuro.01.2009.11.106